tramadol

Tramadol Hydrochloride Tablet, Tramadol 50mg Overdose

Tramadol hydrochloride is the generic name for the brand pain reliever known to everybody as Ultarum. Tramadol hydrochloride 50 mg is a central acting analgesic in an orally disintegrating formulation using a Flashtab tablet formulation base. Although its mode of action is not completely understood, from animal tests, at least two complementary mechanisms appear applicable: binding of parent and M1 metabolite to u-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin. Tramadol has been shown to inhibit reuptake of norepinephrine and serotonin in vitro, as have some other opioid analgesics. These mechanisms may contribute independently to the overall profile of tramadol. Analgesia in humans begins approximately within one hour after administration and reaches a peak in approximately two or three hours.


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Tramadol  hydrochloride is a centrally acting synthetic opioid analgesic, effective in the treatment of pain. Tramadol's minimal propensity to induce adverse effects is an advantage over morphine-like agents. Relative to morphine, this medication causes less dependence and less respiratory depression.

Tramadol hydrochloride is currently available under the brand name Ultram, and in several generic formulations. Branded and generic formulations of tramadol are indicated for the management of moderate to moderately severe pain, and may be dosed four to six times per day, not to exceed 400mg.

This medication work best if taken as per the suggested dosage by your physician. Never take over dosage of this medication  as it results in serious side effects that some times prove fatal.

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Last Modified: Wednesday, September 6, 2006
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